Publications

Publications of members of the department of Eukaryote Genetics since 2005

Publications

Publications Prof. Jörn Lausen

  1. Godavarthy PS, Kumar R, Herkt SC, Pereira RS, Hayduk N, Weissenberger ES, Aggoune D, Manavski Y, Lucas T, Pan KT, Voutsinas JM, Wu Q, Müller MC, Saussele S, Oellerich T, Oehler VG, Lausen J, Krause DS. The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis. 

Haematologica. 2020 Jan; 105(1):136-147.doi: 103324/haematol.2018.212365.  Epub 2019 Apr 24.
PMID: 31018977

  2. Windisch R, Pirschtat N, Kellner C, Chen-Wichmann L, Lausen J, Humpe A, Krause          DS, Wichmann C. Oncogenic  Deregulation of Cell Adhesion Molecules in Leukemia. 

Cancers (Basel). 2019 Mar 5;11(3). pii: E311. doi: 10.3390/cancers11030311. Review. PMID:30841639

  1. Steiner, M.; Schneider, L.; Yillah, J.; Gerlach, K.; Kuvardina, O.N.; Meyer, A.; Maring, A.; Bonig, H.; Seifried, E.;, Zörnig, M.; Lausen, J. FUSE binding protein 1 (FUBP1) expression is upregulated by T-cell acute lymphocytic leukemia protein 1 (TAL1) and required for efficient erythroid differentiation.

PLoS One. 2019 Jan 17;14(1). (IF: 2.8)

  1. Chen-Wichmann, L.; Shvartsman, M.; Preiss, C.; Hockings, C.; Windisch, R, Redondo Monte E, Leubolt G, Spiekermann K, Lausen J, Brendel C, Grez M.; Greif, P.A.; Wichmann, C. Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion.

Oncogene. 2019 Jan;38(2):261-272. (IF: 6.854)

  1. Kramer, J.; Désor, V.; Brunst, S.; Wittmann, S.K.; Lausen, J.; Heering, J.; Proschak, A. and Proschak, E. A coupled fluorescence-based assay for the detection of protein arginine N-methyltransferase 6 (PRMT6) enzymatic activity.

Anal Biochem. 547: 7-13. 2018 (IF: 2.24)

  1. Herkt S.; Kuvardina, O.N.; Herglotz, J.; Schneider, L.; Meyer, A.; Pommerenke, C.; Salinas-Riester, G.; Seifried, E.; Bonig, H.; Lausen, J. Protein arginine methyltransferase 6 controls erythroid gene expression and differentiation of human CD34+ progenitor cells.

Haematologica. 103(1): 18-29. 2018 (IF: 9.09)

  1. Kuvardina, O.N.; Herkt, S.; Meyer, A.; Schneider, L.; Yillah, J.; Kohrs, N.; Bonig, H.; Seifried, E.; Müller-Tidow, C.; Lausen, J. Hematopoietic transcription factors and differential cofactor binding regulate PRKACB isoform expression.

Oncotarget. 8(42): 71685-71698. 2017. (IF: 5.168)

  1. Schanda, J.; Lee, C.W.; Wohlan, K.; Müller-Kuller, U.; Kunkel, H.; Quagliano-Lo Coco, I.; Stein, S.; Metz, A.; Koch, J.; Lausen, J.; Platzbecker, U.; Medyouf, H.; Gohlke, H.; Heuser, M.; Eder, M.; Grez, M.; Scherr, M.; Wichmann, C. Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.

Haematologica, 102(5): e170-e174. 2017 (IF: 9.09)

  1. Kohrs, N.; Kolodziej, S.; Kuvardina, O.N.; Herglotz, J.; Yillah, J.; Herkt, S.; Piechatzek, A.; Salinas-Riester, G.; Lingner, T.; Wichmann, C.; Bonig, H.; Seifried, E.; Platzbecker, U.; Medyouf, H.; Grez, M. and Lausen, J.: MiR144/451 expression is repressed by RUNX1 during megakaryopoiesis and disturbed by RUNX1/ETO.

PLoS Genet.,12(3): e1005946. 2016. (IF: 6.661)

  1. Kuvardina, O.N.; Herglotz, J.; Kolodziej, S.; Kohrs, N.; Wojcik, B.; Oellerich, T.; Corso, J.; Behrens, K.; Kumar, A.; Hussong, H.; Urlaub, H; Koch, J.; Serve, H.; Bonig, H.; Stocking, C.; Rieger, M.; Lausen, J.: RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation. 

Blood, 125(23): 3570-9. 2015. (IF: 13.164)

  1. Ponnusamy, K.; Kohrs, N.; Ptasinska, A.; Assi, S.; Herold, T.; Weigert, O.; Hiddemann, W.; Lausen, J.; Bonifer, C.; Henschler, R.; Wichmann, C.: RUNX1/ETO blocks selection binding via transcriptional repression of PSGL-1.

Oncogenesis, 4:e146. 2015. (IF: 5.021)

  1. Müller-Kuller, U.; Ackermann M.; Kolodziej, S.; Brendel, C.; Fritsch, J.;Lachmann, N.; Kunkel, H.; Lausen, J.; Schambach, A.; Moritz, T.; Grez, M.: A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.

Nucleic Acids Research, 18;43(3):1577-92. 2015. (IF: 10.162)

  1. Ponnusamy, K.; Chen-Wichmann, L.; Kuvardina, O.N.; Lausen, J.; Henschler, R.; Wichmann, C. The truncated Runx1/Eto activates Vla-4-dependent adhesion and migration of hematopoietic progenitor cells

Haematologica, 99(12):e253-6. 2014. (IF: 9.09)

  1. Kolodziej, S.; Kuvardina, O.N.; Oellerich T.; Herglotz, J.; Backert, I.; Kohrs, N.; Buscató, E.; Wittmann, S.K.; Salinas-Riester, G.; Bonig, H.; Karas, M.; Serve, H.; Proschak, E.; Lausen, J.: PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation.

Nature Communications, 5: 3995. 2014. (IF: 12.124)

  1. Ng, K.P.; Hu, Z.; Ebrahem, Q.; Negrotto, S.; Lausen, J.; Saunthararajah, Y. Runx1 deficiency permits granulocyte lineage commitment but impairs subsequent maturation.

Oncogenesis, 2, e78. 2013 (IF: 5.021)

  1. Courtial, N.; Mücke, C.; Herkt, S.; Kolodziej, S.; Hussong H.; Lausen, J. The T-cell oncogene Tal2 is a target of PU.1 and upregulated during osteoclastogenesis.

PLoS ONE, 8(9): e76637. 2013. (IF: 3.54)

  1. Herglotz, J.; Kuvardina, O.N.; Kolodziej, S.; Kumar, A.; Hussong, H.; Grez, M.; Lausen, J. Histone arginine methylation keeps RUNX1 target genes in an intermediate state.

Oncogene, 32(20): 2565-75. 2013. (IF: 7.519)

  1. Courtial, N.; Smink, J.J.; Kuvardina, O.N.; Leutz, A.; Göthert, J.R.; Lausen., J.: Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.

FASEB Journal, 26(2): 523-532. 2012 (IF: 5.498)

  1. Bangert, A.; Cristofanon, S.; Eckhardt, I.; Abhari, B.A.; Kolodziej, S.; Häcker, S.; Vellanki, S.H.K.; Lausen, J.; Debatin, K.M.; Fulda, S. Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.

Oncogene, 31(44): 4677-88. 2012. (IF: 7.519)

  1. Wichmann, C.; Becker, Y.; Chen-Wichmann, L.; Vogel, V.; Vojtkova, A.; Herglotz, J.; Moore, S.; Koch, J.; Lausen, J.; Mäntele, W.; Gohlke, H.; Grez, M.: Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity. 

Blood, 116(4): 603-13. 2010. IF: (13.164)

  1. Lausen, J*.; Pless, O.; Leonard, F.; Kuvardina, O.N.; Koch, B.; Leutz, A.: Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1.

Biol. Chem., 285(8): 5338-46. 2010. (IF: 4.125) *Corresponding author

  1. Pless, O.; Kowenz-Leutz, E.; Knoblich, M.; Lausen, J.; Beyermann, M.; Walsh, M.J.; Leutz, A.: G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta.

Biol. Chem., 283(39): 26357-63, 2008. (IF: 4.125)

  1. Wei, Y.; Liu, S.*; Lausen, J*.; Cho, S.; Biris, N.; Kobayashi, N.; Wei, Y.; Yokoyama, S.; Werner, M.H.: A TAF4-homology domain from the co-repressor Eight Twenty-one (ETO) is a docking platform for positive and negative regulators of transcription. 2007.

Nat. Struct. Mol. Biol., 14(7): 653-661, 2007. *Equal contr. (IF: 12.595)

  1. Erdmann, S.; Senkel, S.; Arndt, T.; Lucas, B.; Lausen, J.; Klein-Hitpass, L.; Ryffel, G.U.; Thomas, H.: The tissue specific transcription factor HNF4a inhi-bits cell proliferation and induces apoptosis in the pancreatic INS-1 b-cell line.

Biol. Chem., 388(1): 91-106. 2007. (IF: 3.273)

  1. Lausen, J.; Liu, S.; Fliegauf, M.; Lubbert, M.; Werner, M.H.: ELA2 is regu-lated by hematopoietic transcription factors, but not repressed by AML1-ETO.

Oncogene, 25(9): 1349-57. 2006. (IF: 7.519)

  1. Lucas, B.; Grigo, K.; Erdmann, S.; Lausen, J.; Klein-Hitpass, L.; Ryffel, G.U.:HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.

Oncogene, 24(42): 6418-31. 2005. (IF: 7.519)

  1. Lausen, J.; Cho, S.; Liu, S.; Werner, M.H.: The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO. J.

Biol. Chem., 279(47): 49281-8. 2004. (IF: 4.125)

  1. Thomas, H.; Badenberg, B.; Bulman, B.; Lemm, I.; Lausen J.; Kind, L.; Roosen, S.; Ellard, S.; Hattersley, A.; Ryffel, G.U.: Evidence for haploinsufficiency of the human HNF1a gene by functional characterization of MODY3-associated mutations.

Biol. Chem., 383: 1691-1700, 2002. IF: (3.273)

  1. Lausen, J.; Thomas, H.; Lemm, I.; Bulman, M.; Borgschulze, M.; Lingott, A.; Hattersley, A.T.; Ryffel, G.U.: Naturally occurring mutations in the human HNF4a gene impair the function of the transcription factor to a varying degree.

Nucleic Acids Research, 28: 430-437. 2000. (IF: 10.162)

  1. Puzio, P.S.; Lausen, J.; Heinen, P.; Grundler, F.M.W.: Promoter analysis of the nematode responsive pyk 20 gene from arabidopsis thaliana.

Plant Science, 157: 245-255. 2000. (IF: 3.76)

  1. Puzio, P.S.; Lausen, J.; Almeida-Engler, J.; Cai, D.; Gheysen, G.; Grundler, F.M.W.: Isolation of a gene from arabidopsis thaliana related to nematode feeding structures.

Gene, 239: 163-172, 1999. (IF: 2.415)

 

2001    Ph.D.-thesis, Dissertation

Title: “Einfluss diabetes-assoziierter Mutationen im Transkriptionsfaktor HNF4a“

 

Review Artikel

  1. Windisch R, Pirschtat N, Kellner C, Chen-Wichmann L, Lausen J, Humpe A, Krause DS, Wichmann C. Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia.

Cancers (Basel). 2019 Mar 5;11(3).

  1. Lausen, J. Contributions of the Histone Arginine Methyltransferase PRMT6 to the Epigenetic Function of RUNX1.

Crit. Rev. Eukaryot Gene Expr., 23(3):265-74. 2013. (IF: 1.66)

  1. Wichmann, C.; Grez, M.; Lausen, J.: Molecular Targeting of Aberrant Transcription Factors in Leukemia: Strategies for RUNX1/ETO.

Current Drug Targets, 11(9): 1181-91. 2010. (IF: 3.236)

Publications of the former IIG

Morabbi Heravi K; Altenbuchner J.(2018) Cross-talk among transporters of the phosphoenolpyruvate-dependent phosphotransferase system in Bacillus subtilis. J Bacteriol. pii: JB.00213-18. doi: 10.1128/JB.00213-18. (Link) 

Kautzmann F; Altenbuchner J.(2017) Inactivation of genes involved in base excision repair of Corynebacterium glutamicum and survival of the mutants in presence of various mutagens. Arch Microbiol.199(7):1043-1054. doi: 10.1007. (Link)

Reuß DR1, Altenbuchner J2, Mäder U3, Rath H3, Ischebeck T4, Sappa PK3, Thürmer A5, Guérin C6, Nicolas P6, Steil L3, Zhu B1, Feussner I4,7, Klumpp S8, Daniel R5,7, Commichau FM1,7, Völker U3, Stülke J1,7 (2017) Large-scale reduction of the Bacillus subtilis genome: consequences for the transcriptional network, resource allocation, and metabolism.Genome Res. 2017 Feb;27(2):289-299. doi: 10.1101/gr.215293.116. (Link)
 

Wang, L.; Hoffmann, J.; Watzlawick, H.; Altenbuchner, J. (2016): Markerless Gene Deletion with Cytosine Deaminase in Thermus thermophilus Strain HB27. In: Appl Environ Microbiol 82 (4), S. 1249–1255.(Link)

Dobruchowska JM1, Jonsson JO2, Fridjonsson OH2, Aevarsson A3, Kristjansson JK3, Altenbuchner J4, Watzlawick H4, Gerwig GJ1,5, Dijkhuizen L1, Kamerling JP1,5, Hreggvidsson GO6,7 (2016) Modification of linear (β1→3)-linked gluco-oligosaccharides with a novel recombinant β-glucosyltransferase (trans-β-glucosidase) enzyme from Bradyrhizobium diazoefficiens. Glycobiology. 2016 1157-1170. doi: 10.1093

 
K. Morabbi Heravi, J. Lange, H. Watzlawick, J. Kalinowski, J. Altenbuchner (2015) Transcriptional Regulation of the Vanillate Utilization Genes ( vanABKOperon) of Corynebacterium glutamicumby VanR, a PadR-Like Repressor. J. Bacteriol. 197 (5): 959-972 (Link)


Daniel R. Reuß, Jörg Schuldes, Rolf Daniel, Josef Altenbuchner (2015) Complete Genome Sequence of Bacillus subtilis subsp. subtilis Strain 3NA. Genome Announc. (Link)

J. Hoffmann, J. Altenbuchner (2014) Hyaluronic acid production with Corynebacterium glutamicum: effect of media composition on yield and molecular weight. J. Appl. Microbiol. 117 (3): 663-78 (Link)


K. Morabbi Heravi, J. Altenbuchner (2014) Regulation of the Bacillus subtilis mannitol utilization genes: Promoter structure and transcriptional activation by the wild-type regulator (MtlR) and its mutant. Microbiology. 160 (Pt 1): 91-101

N. Graf, J. Altenbuchner (2014)  Genetic engineering of Pseudomonas putida KT2440 for rapid and high-yield production of vanillin from ferulic acid (2014) Applied Microbiology and Biotechnology 98(1):137-149

L. Wang, H. Watzlawick, O. Fridjonsson, G. Hreggvidsson, J. Altenbuchner (2013) Improved soluble expression of the gene encoding amylolytic enzyme Amo45 by fusion with the mobile-loop-region of co-chaperonin GroES in Escherichia coli.  Biocatalysis and Biotransformation 31(6):335-342


S. Söllner, M. Rahnert, M. Siemann-Herzberg, R. Takors, J. Altenbuchner (2013) Evolution of pyruvate kinase-deficient Escherichia coli mutants enables glycerol-based cell growth and succinate production. Journal of Applied Microbiology 115(6):1368-1378

L. Warth, J. Altenbuchner (2013) The tyrosine recombinase MrpA and its target sequence: a mutational analysis of the recombination site mrpS resulting in a new left element/right element (LE/RE) deletion system. Arch Microbiol. 195(9):617-636

N. Graf, J. Altenbuchner (2013) Functional characterization and application of a tightly regulated MekR/PmekA expression system in Escherichia coli and Pseudomonas putida. Applied Microbiology and Biotechnology 97(18):8239-8251

M. Wenzel, J. Altenbuchner (2013) The Bacillus subtilis mannose regulator, ManR, a DNA-binding protein regulated by HPr and its cognate PTS transporter, ManP.  Molecular Microbiology 88(3):562-576

L. Warth, J. Altenbuchner (2013) A new site-specific recombinase-mediated system for targeted multiple genomic deletions employing chimeric loxP and mrpS sites. Applied Microbiology and Biotechnology 97(15):6845-6856

B. Mückschel, O. Simon, J. Klebensberger, N. Graf, B. Rosche, J. Altenbuchner, J. Pfannstiel, A. Huber, B. Hauer (2012) Ethylene Glycol Metabolism of Pseudomonas putida. Appl Environ Microbiol. 78(24):8531-8539


J. Birke, N. Hambsch, G. Schmitt, J. Altenbuchner, D. Jendrossek (2012) Phe317 is essential for rubber oxigenase RoxA activity.  Appl Environ Microbiol. 78(22):7876-7883

J. Hoffmann, J. Bóna-Lovász, H. Beuttler, J. Altenbuchner (2012, Aug 17) In vivo and in vitro studies on the carotenoid cleavage oxygenases from Sphingopyxis alaskensis RB2256 and Plesiocystis pacifica SIR-1 revealed their substrate specificities and non-retinal-forming cleavage activities. FEBS J.

M. Schrallhammer, S. Galati, J. Altenbuchner, M. Schweikert, H.-D. Görtz, G. Petroni (2012, Feb 20) Tracing the role of R-bodies in the killer trait: Absence of toxicity of R-body producing recombinant E. coli on paramecia. Eur J Protistol.

International Patent WO2012/013710 / PCT/EP2011/062921: "Regulation of inducible promoters"; Feb 2012. Lonza AG, M. Wenzel, J. Altenbuchner, C. Kiziak

K. Morabbi Heravi, M. Wenzel, J. Altenbuchner (2011) Regulation of mtl operon promoter of Bacillus subtilis: Requirements of its use in expression vectors. Microbial Cell Factories, 10:83


M. Wenzel, A. Müller, M. Siemann-Herzberg, and J. Altenbuchner (2011) Self-inducible Bacillus subtilis expression system enables the reliable and inexpensive protein production by high-cell-density fermentation. Appl Environ Microbiol.77(18):6419-6425

N. Graf, J. Altenbuchner (2011) Development of a method for markerless gene deletion in Pseudomonas putida. Appl Environ Microbiol. 77(15):5549-5552

L. Warth, I. Haug, J. Altenbuchner (2011) Characterization of the tyrosine recombinase MrpA encoded by the Streptomyces coelicolor A3(2) plasmid SCP2*.Archives of Microbiology193(3):187-200

H. Beuttler, J. Hoffmann, M. Jeske, B. Hauer, R. D. Schmid, J. Altenbuchner, and V. B. Urlacher (2011) Biosynthesis of zeaxanthin in recombinant Pseudomonas putida. Applied Microbiology and Biotechnology 89:1137-1147

H. Motejadded, B. Kranz, S. Berensmeier, M. Franzreb, and J. Altenbuchner (2010) Expression, one-step purification, and immobilization of HaloTag™ fusion proteins on chloroalkane-functionalized magnetic beads. Applied Biochemistry and Biotechnology 162:2098-2110


T. Q. Sun and J. Altenbuchner (2010) Characterization of a mannose utilization system in Bacillus subtilis. Journal of Bacteriology 192:2128-2139

M. Jeske and J. Altenbuchner (2010) The Escherichia coli rhamnose promoter rhaPBAD is in Pseudomonas putida KT2440 independent of Crp-cAMP activation. Applied Microbiology and Biotechnology 85:1923-1933

International Patent WO/2011/018377 / PCT/EP2010/061195: "Fermentation process"; Sept. 2010. Lonza AG, M.Wenzel, J. Altenbuchner, C. Kiziak, M. Siemann-Herzberg

H. Lößner, S. Leschner, A. Endmann, K. Westphal, K. Wolf, K. Kochrübe, T. Miloud, J. Altenbuchner, and S. Weiss (2009) Drug-inducible remote control of gene expression by probiotic Escherichia coli Nissle 1917 in intestine, tumor and gall bladder of mice. Microbes and Infection 11:1097-1105


O. Sosedov, K. Matzer, S. Burger, C. Kiziak, S. Baum, J. Altenbuchner, A. Chmura, F. van Rantwijk, and A. Stolz (2009) Construction of recombinant Escherichia coli catalysts which simultaneously express an (S)-oxynitrilase and different nitrilase variants for the synthesis of (S)-mandelic acid and (S)-mandelic amide from benzaldehyde and cyanide. Advanced Synthesis & Catalysis 35:1531-1538

H. Motejadded and J. Altenbuchner (2009) Construction of a dual-tag system for gene expression, protein affinity purification and fusion protein processing. Biotechnology Letters3:543-549

C. Tolzer, S. Pal, H. Watzlawick, J. Altenbuchner, and K. Niefind (2009) Crystallization and preliminary crystallographic analysis of cgHle, a homoserine acetyltransferase homologue, from Corynebacterium glutamicum. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 65:34-38

H. Watzlawick and R. Mattes (2009) Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45. Applied and Environmental Microbiology 75:7026-7036

G. Placier, H. Watzlawick, C. Rabiller, and R. Mattes (2009) Evolved beta-galactosidases from Geobacillus stearothermophilus with improved transgalactosylation yield for galacto-oligosaccharide production. Applied and Environmental Microbiology75:6312-6321

S. Ravaud, X. Robert, H. Watzlawick, R. Haser, R. Mattes, and N. Aghajari (2009) Structural determinants of product specificity of sucrose isomerases.   Febs Letters583:1964-1968

S. Rustler, H. Motejadded, J. Altenbuchner, and A. Stolz (2008) Simultaneous expression of an arylacetonitrilase from Pseudomonas fluorescens and a (S)-oxynitrilase from Manihot esculenta in Pichia pastoris for the synthesis of (S)-mandelic acid. Applied Microbiology and Biotechnology 80:87-97


R. Dürr, A. Neumann, O. Vielhauer, J. Altenbuchner, S. G. Burton, D. A. Cowan, and C. Syldatk (2008) Genes responsible for hydantoin degradation of a halophilic Ochrobactrum sp G21 and Delftia sp 124 - New insight into relation of D-hydantoinases and dihydropyrimidinases. Journal of Molecular Catalysis B-Enzymatic 52-3:2-12

A. Wegerer, T. Q. Sun, and J. Altenbuchner (2008) Optimization of an E. coli L-rhamnose-inducible expression vector: test of various genetic module combination.  BMC Biotechnology 8

A. Völker, A. Kirschner, U. T. Bornscheuer, and J. Altenbuchner (2008) Functional expression, purification, and characterization of the recombinant Baeyer-Villiger monooxygenase MekA from Pseudomonas veronii MEK700. Applied microbiology and biotechnology 77:1251-1260

S. Ravaud, X. Robert, H. Watzlawick, S. Laurent, R. Haser, R. Mattes, and N. Aghajari (2008) Insights into sucrose isomerization from crystal structures of the Pseudomonas mesoacidophila MX-45 sucrose isomerase, MutB. Biocatalysis and Biotransformation 26:111-119

L. Wang, W. Armbruster, D. Jendrossek (2007) Production of medium-chain-length hydroxyalkanoic acids from Pseudomonas putida in pH stat. Applied Microbiology and Biotechnology July 2007, Volume 75, Issue 5, pp 1047-1053


A. Kirschner, J. Altenbuchner, and U. T. Bornscheuer (2007) Design of a secondary alcohol degradation pathway from Pseudomonas fluorescens DSM 50106 in an engineered Escherichia coli. Applied Microbiology and Biotechnology 75:1095-1101

C. Onaca, M. Kieninger, K. H. Engesser, and J. Altenbuchner (2007) Degradation of alkyl methyl ketones by Pseudomonas veronii MEK700. Journal of Bacteriology 189:3759-3767

A. Kirschner, J. Altenbuchner, and U. T. Bornscheuer (2007) Cloning, expression, and characterization of a Baeyer-Villiger monooxygenase from Pseudomonas fluorescens DSM 50106 in E. coli.Applied Microbiology and Biotechnology 73:1065-1072

S. Ravaud, X. Robert, H. Watzlawick, R. Haser, R. Mattes, and N. Aghajari (2007) Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. Journal of Biological Chemistry 282:28126-28136

H. Motejadded, J. Altenbuchner (2007) Integration of a lipase gene into Bacillus subtilis chromosome: Recombinant strains without antibiotic resistance marker. Iranian Journal of Biotechnology 5: 105-109

H. Gröger, O. May, H. Werner, A. Menzel, and J. Altenbuchner (2006) A "Second-Generation process" for the synthesis of L-neopentylglycine: Asymmetric reductive amination using a recombinant whole cell catalyst. Organic Process Research & Development10:666-669


A. Keck, D. Conradt, A. Mahler, A. Stolz, R. Mattes, and J. Klein (2006) Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6. Microbiology 152:1929-1940

M. Foucault, H. Watzlawick, R. Mattes, R. Haser, and P. Gouet (2006) Crystallization and preliminary X-ray diffraction studies of two thermostable alpha-galactosidases from glycoside hydrolase family 36. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 62:100-103

S. Ravaud, H. Watzlawick, R. Haser, R. Mattes, and N. Aghajari (2006) Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 62:74-76

T. Stumpp, S. Himbert, and J. Altenbuchner (2005) Cloning of the netropsin resistance genes from Streptomyces flavopersicus NRRL 2820. Journal of Basic Microbiology 45:355-362


B. Apichaisataienchote, J. Altenbuchner, and H. Buchenauer (2005) Isolation and identification of Streptomyces fradiae SU-1 from Thailand and protoplast transformation with the chitinase B gene from Nocardiopsis prasina OPC-131. Current Microbiology 51:116-121

S. Ravaud, H. Watzlawick, R. Mattes, R. Haser, and N. Aghajari (2005) Towards the three-dimensional structure of a sucrose isomerase from Pseudomonas mesoacidophila MX-45. Biologia 60:89-95

C. Kiziak, D. Conradt, A. Stolz, R. Mattes, and J. Klein (2005) Nitrilase from Pseudomonas fluorescens EBC191: cloning and heterologous expression of the gene and biochemical characterization of the recombinant enzyme. Microbiology 151:3639-3648c

S. Ravaud, H. Watzlawick, R. Haser, R. Mattes, and N. Aghajari (2005) Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 61:100-103

Publikationen
To the top of the page